Micropshere Agent Used with Echocardiography Provides Results Comparable to SPECT
|
By MedImaging International staff writers Posted on 25 Feb 2009 |
|
A new study concluded that a new microsphere contrast agent used in echocardiography is well tolerated, and that its diagnostic performance in chest pain patients is comparable with single photon emission computed tomography (SPECT) perfusion imaging.
Acusphere, Inc. (Watertown, MA, USA) reported that the study summarized the phase III clinical trial results for Imagify (perflubutane polymer microspheres) for injectable suspension, a cardiovascular drug for the detection of coronary artery disease, the leading cause of death in the United States.
The study was led by Dr. Roxy Senior, consultant cardiologist and director of cardiac research, department of cardiovascular medicine and Institute of Postgraduate Medical Education and Research at Northwick Park Hospital (Harrow, Middlesex, UK), among others. Dr. Senior was the lead clinical investigator for Acusphere's clinical trials for Imagify.
Acusphere is a specialty pharmaceutical company that develops new drugs and improved formulations of existing drugs using its proprietary microsphere technology. The company's lead product candidate, Imagify, is a cardiovascular drug for the detection of coronary artery disease, the leading cause of death in the United States, for which a New Drug Application (NDA) was submitted to the U.S. Food & Drug Administration (FDA) in April 2008 and filed in June 2008. Imagify is designed to enable ultrasound to compete more effectively with nuclear stress testing, the leading procedure for detecting coronary artery disease.
It is estimated that more than 10 million procedures are done each year in the United States to detect coronary artery disease. Imagify and the company's other product candidates were created using proprietary technology that enables Acusphere to control the porosity and size of nanoparticles and microspheres in a versatile manner that allows them to be customized to address the delivery needs of a variety of drugs.
The study was published in the January 2009 issue of the European Journal of Echocardiography.
Related Links:
Acusphere
Northwick Park Hospital
Acusphere, Inc. (Watertown, MA, USA) reported that the study summarized the phase III clinical trial results for Imagify (perflubutane polymer microspheres) for injectable suspension, a cardiovascular drug for the detection of coronary artery disease, the leading cause of death in the United States.
The study was led by Dr. Roxy Senior, consultant cardiologist and director of cardiac research, department of cardiovascular medicine and Institute of Postgraduate Medical Education and Research at Northwick Park Hospital (Harrow, Middlesex, UK), among others. Dr. Senior was the lead clinical investigator for Acusphere's clinical trials for Imagify.
Acusphere is a specialty pharmaceutical company that develops new drugs and improved formulations of existing drugs using its proprietary microsphere technology. The company's lead product candidate, Imagify, is a cardiovascular drug for the detection of coronary artery disease, the leading cause of death in the United States, for which a New Drug Application (NDA) was submitted to the U.S. Food & Drug Administration (FDA) in April 2008 and filed in June 2008. Imagify is designed to enable ultrasound to compete more effectively with nuclear stress testing, the leading procedure for detecting coronary artery disease.
It is estimated that more than 10 million procedures are done each year in the United States to detect coronary artery disease. Imagify and the company's other product candidates were created using proprietary technology that enables Acusphere to control the porosity and size of nanoparticles and microspheres in a versatile manner that allows them to be customized to address the delivery needs of a variety of drugs.
The study was published in the January 2009 issue of the European Journal of Echocardiography.
Related Links:
Acusphere
Northwick Park Hospital
Radiology Software
DxWorks
Portable X-ray Unit
AJEX140H
Portable Color Doppler Ultrasound System
S5000
Computed Tomography System
Aquilion ONE / INSIGHT Edition
Latest Nuclear Medicine News
- Novel Radiolabeled Antibody Improves Diagnosis and Treatment of Solid Tumors
- Novel PET Imaging Approach Offers Never-Before-Seen View of Neuroinflammation
- Novel Radiotracer Identifies Biomarker for Triple-Negative Breast Cancer
- Innovative PET Imaging Technique to Help Diagnose Neurodegeneration
- New Molecular Imaging Test to Improve Lung Cancer Diagnosis
- Novel PET Technique Visualizes Spinal Cord Injuries to Predict Recovery
- Next-Gen Tau Radiotracers Outperform FDA-Approved Imaging Agents in Detecting Alzheimer’s
- Breakthrough Method Detects Inflammation in Body Using PET Imaging
- Advanced Imaging Reveals Hidden Metastases in High-Risk Prostate Cancer Patients
- Combining Advanced Imaging Technologies Offers Breakthrough in Glioblastoma Treatment
- New Molecular Imaging Agent Accurately Identifies Crucial Cancer Biomarker
- New Scans Light Up Aggressive Tumors for Better Treatment
- AI Stroke Brain Scan Readings Twice as Accurate as Current Method
- AI Analysis of PET/CT Images Predicts Side Effects of Immunotherapy in Lung Cancer
- New Imaging Agent to Drive Step-Change for Brain Cancer Imaging
- Portable PET Scanner to Detect Earliest Stages of Alzheimer’s Disease
Channels
Radiography
view channel
Machine Learning Algorithm Identifies Cardiovascular Risk from Routine Bone Density Scans
A new study published in the Journal of Bone and Mineral Research reveals that an automated machine learning program can predict the risk of cardiovascular events and falls or fractures by analyzing bone... Read more
AI Improves Early Detection of Interval Breast Cancers
Interval breast cancers, which occur between routine screenings, are easier to treat when detected earlier. Early detection can reduce the need for aggressive treatments and improve the chances of better outcomes.... Read more
World's Largest Class Single Crystal Diamond Radiation Detector Opens New Possibilities for Diagnostic Imaging
Diamonds possess ideal physical properties for radiation detection, such as exceptional thermal and chemical stability along with a quick response time. Made of carbon with an atomic number of six, diamonds... Read more
MRI
view channel
Cutting-Edge MRI Technology to Revolutionize Diagnosis of Common Heart Problem
Aortic stenosis is a common and potentially life-threatening heart condition. It occurs when the aortic valve, which regulates blood flow from the heart to the rest of the body, becomes stiff and narrow.... Read more
New MRI Technique Reveals True Heart Age to Prevent Attacks and Strokes
Heart disease remains one of the leading causes of death worldwide. Individuals with conditions such as diabetes or obesity often experience accelerated aging of their hearts, sometimes by decades.... Read more
AI Tool Predicts Relapse of Pediatric Brain Cancer from Brain MRI Scans
Many pediatric gliomas are treatable with surgery alone, but relapses can be catastrophic. Predicting which patients are at risk for recurrence remains challenging, leading to frequent follow-ups with... Read more
AI Tool Tracks Effectiveness of Multiple Sclerosis Treatments Using Brain MRI Scans
Multiple sclerosis (MS) is a condition in which the immune system attacks the brain and spinal cord, leading to impairments in movement, sensation, and cognition. Magnetic Resonance Imaging (MRI) markers... Read moreNuclear Medicine
view channel
Novel Radiolabeled Antibody Improves Diagnosis and Treatment of Solid Tumors
Interleukin-13 receptor α-2 (IL13Rα2) is a cell surface receptor commonly found in solid tumors such as glioblastoma, melanoma, and breast cancer. It is minimally expressed in normal tissues, making it... Read more
Novel PET Imaging Approach Offers Never-Before-Seen View of Neuroinflammation
COX-2, an enzyme that plays a key role in brain inflammation, can be significantly upregulated by inflammatory stimuli and neuroexcitation. Researchers suggest that COX-2 density in the brain could serve... Read more
General/Advanced Imaging
view channel
AI-Based CT Scan Analysis Predicts Early-Stage Kidney Damage Due to Cancer Treatments
Radioligand therapy, a form of targeted nuclear medicine, has recently gained attention for its potential in treating specific types of tumors. However, one of the potential side effects of this therapy... Read more
CT-Based Deep Learning-Driven Tool to Enhance Liver Cancer Diagnosis
Medical imaging, such as computed tomography (CT) scans, plays a crucial role in oncology, offering essential data for cancer detection, treatment planning, and monitoring of response to therapies.... Read more
Imaging IT
view channel
New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible
Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology
The global artificial intelligence (AI) in medical diagnostics market is expanding with early disease detection being one of its key applications and image recognition becoming a compelling consumer proposition... Read more
Industry News
view channel
GE HealthCare and NVIDIA Collaboration to Reimagine Diagnostic Imaging
GE HealthCare (Chicago, IL, USA) has entered into a collaboration with NVIDIA (Santa Clara, CA, USA), expanding the existing relationship between the two companies to focus on pioneering innovation in... Read more
Patient-Specific 3D-Printed Phantoms Transform CT Imaging
New research has highlighted how anatomically precise, patient-specific 3D-printed phantoms are proving to be scalable, cost-effective, and efficient tools in the development of new CT scan algorithms... Read more
Siemens and Sectra Collaborate on Enhancing Radiology Workflows
Siemens Healthineers (Forchheim, Germany) and Sectra (Linköping, Sweden) have entered into a collaboration aimed at enhancing radiologists' diagnostic capabilities and, in turn, improving patient care... Read more