Imaging Solution Improves Stroke Image Interpretation
By MedImaging International staff writers Posted on 02 Jul 2019 |
Image: The e-CTA software aids consistent mechanical thrombectomy patient selection (Photo courtesy of Brainomix).
A novel CT angiography (CTA) imaging solution improves inter-rater consistency and reliability, helping the selection of patients that can benefit the most from mechanical thrombectomy.
The Brainomix (Oxford, United Kingdom) e-CTA software is designed to provide fast, consistent, and fully automated calculation of the CTA collateral score (CTA-CS), using artificial intelligence (AI) and deep learning algorithms to analyze the images. In a clinical validation study, researchers at the University of Oxford (United Kingdom) categorized the degree of collateral flow in 98 patients, generating a CTA-CS score for each one. The results of the e-CTA software were then compared to a reference standard consensus opinion by from three expert neuroradiologists.
The agreement between individual neuroradiologists, both with and without the automated e-CTA reference was then quantified, and the effect of e-CTA on inter-rater reliability was assessed. The results demonstrated a high degree of agreement between the fully automated and objective e-CTA score and the consensus expert CTA-CS. The addition of an e-CTA assisted neuroradiological grading of collateral scores further reduced expert variability. CTA-CS and e-CTA scores correlated with the demonstrated deleterious effect of poor collateral blood flow on tissue survival. The study was published on June 19, 2019, in Cerebrovascular Disease.
“The importance of good collateral blood flow for patient outcome in acute stroke treatment is well recognized. However, even expert collateral scores commonly suffer from inter-rater error. e-CTA improved consistency between neuroradiologists when used as a decision support tool,” said George Harston, chief medical and innovation officer at Brainomix. “Even when used as a standalone tool, e-CTA produced similar scores compared to experts, opening up the opportunity for reliable collateral assessment for all patients, regardless of which hospital they attend.”
Timely restoration of cerebral blood flow using reperfusion therapy is the most effective maneuver for salvaging ischemic brain tissue that is not already infracted. Intravenous alteplase is first-line therapy, provided that treatment is initiated within 4.5 hours of clearly defined symptom onset. Mechanical thrombectomy is indicated for patients with acute ischemic stroke, due to a large artery occlusion in the anterior circulation, who can be treated within 24 hours of the time last known to be well, regardless of whether they receive intravenous alteplase for the same ischemic stroke event.
Related Links:
Brainomix
University of Oxford
The Brainomix (Oxford, United Kingdom) e-CTA software is designed to provide fast, consistent, and fully automated calculation of the CTA collateral score (CTA-CS), using artificial intelligence (AI) and deep learning algorithms to analyze the images. In a clinical validation study, researchers at the University of Oxford (United Kingdom) categorized the degree of collateral flow in 98 patients, generating a CTA-CS score for each one. The results of the e-CTA software were then compared to a reference standard consensus opinion by from three expert neuroradiologists.
The agreement between individual neuroradiologists, both with and without the automated e-CTA reference was then quantified, and the effect of e-CTA on inter-rater reliability was assessed. The results demonstrated a high degree of agreement between the fully automated and objective e-CTA score and the consensus expert CTA-CS. The addition of an e-CTA assisted neuroradiological grading of collateral scores further reduced expert variability. CTA-CS and e-CTA scores correlated with the demonstrated deleterious effect of poor collateral blood flow on tissue survival. The study was published on June 19, 2019, in Cerebrovascular Disease.
“The importance of good collateral blood flow for patient outcome in acute stroke treatment is well recognized. However, even expert collateral scores commonly suffer from inter-rater error. e-CTA improved consistency between neuroradiologists when used as a decision support tool,” said George Harston, chief medical and innovation officer at Brainomix. “Even when used as a standalone tool, e-CTA produced similar scores compared to experts, opening up the opportunity for reliable collateral assessment for all patients, regardless of which hospital they attend.”
Timely restoration of cerebral blood flow using reperfusion therapy is the most effective maneuver for salvaging ischemic brain tissue that is not already infracted. Intravenous alteplase is first-line therapy, provided that treatment is initiated within 4.5 hours of clearly defined symptom onset. Mechanical thrombectomy is indicated for patients with acute ischemic stroke, due to a large artery occlusion in the anterior circulation, who can be treated within 24 hours of the time last known to be well, regardless of whether they receive intravenous alteplase for the same ischemic stroke event.
Related Links:
Brainomix
University of Oxford
Latest General/Advanced Imaging News
- Bone Density Test Uses Existing CT Images to Predict Fractures
- AI Predicts Cardiac Risk and Mortality from Routine Chest CT Scans
- Radiation Therapy Computed Tomography Solution Boosts Imaging Accuracy
- PET Scans Reveal Hidden Inflammation in Multiple Sclerosis Patients
- Artificial Intelligence Evaluates Cardiovascular Risk from CT Scans
- New AI Method Captures Uncertainty in Medical Images
- CT Coronary Angiography Reduces Need for Invasive Tests to Diagnose Coronary Artery Disease
- Novel Blood Test Could Reduce Need for PET Imaging of Patients with Alzheimer’s
- CT-Based Deep Learning Algorithm Accurately Differentiates Benign From Malignant Vertebral Fractures
- Minimally Invasive Procedure Could Help Patients Avoid Thyroid Surgery
- Self-Driving Mobile C-Arm Reduces Imaging Time during Surgery
- AR Application Turns Medical Scans Into Holograms for Assistance in Surgical Planning
- Imaging Technology Provides Ground-Breaking New Approach for Diagnosing and Treating Bowel Cancer
- CT Coronary Calcium Scoring Predicts Heart Attacks and Strokes
- AI Model Detects 90% of Lymphatic Cancer Cases from PET and CT Images
- Breakthrough Technology Revolutionizes Breast Imaging