Coronary CTA Using DLR and Subtraction Technique Reduces Radiation Exposure, Improves Image Quality
|
By MedImaging International staff writers Posted on 12 Aug 2022 |
|
Coronary CTA with hybrid iterative reconstruction (HIR) is prone to false-positive results for in-stent restenosis due to stent-related blooming artifact. Now, a new study has found that the combination of deep-learning reconstruction (DLR) and a subtraction technique yielded optimal diagnostic performance for the detection of in-stent restenosis by coronary CTA.
The study was conducted by researchers at Peking Union Medical College Hospital (Beijing, China) to assess the impact of DLR, subtraction images, and combination of DLR and subtraction images on diagnostic performance of coronary CTA for detection of in-stent restenosis. Between March 2020 and August 2021, the research team studied 30 patients (22 men, 8 women; mean age, 63.6 years) with a total of 59 coronary stents who underwent coronary CTA using the two-breath-hold technique (i.e., non-contrast and contrast-enhanced acquisitions). Conventional and subtraction images were reconstructed for hybrid iterative reconstruction (HIR) and DLR, while maximum visible in-stent lumen diameter was measured. Two readers independently evaluated images for in-stent restenosis (≥50% stenosis). A simulated assessment of combined conventional and subtraction images was generated, reflecting assessment of conventional and subtraction images in the presence or absence of severe misregistration artifact, respectively. Invasive angiography served as reference standard.
The researchers found that ultimately, coronary CTA using DLR and subtraction technique - with a combined (conventional and subtraction images) interpretation - yielded PPV, NPV, and accuracy for in-stent restenosis for reader 1 of 73.3%, 93.2%, and 88.1%, and for reader 2 of 75.0%, 84.3%, and 83.1%, respectively. Noting that these findings could guide patient selection for invasive coronary stent evaluation, combining DLR with a two-breath-hold subtraction technique “may help overcome challenges related to stent-related blooming artifact,” according to corresponding author Yi-Ning Wang. Acknowledging that the two-breath-hold subtraction technique requires an additional non-contrast acquisition (and thus a higher radiation dose), “DLR allows a reduction in radiation exposure, while improving image quality,” wrote the authors.
Related Links:
Peking Union Medical College Hospital
Latest General/Advanced Imaging News
- Radiation Therapy Computed Tomography Solution Boosts Imaging Accuracy
- PET Scans Reveal Hidden Inflammation in Multiple Sclerosis Patients
- Artificial Intelligence Evaluates Cardiovascular Risk from CT Scans
- New AI Method Captures Uncertainty in Medical Images
- CT Coronary Angiography Reduces Need for Invasive Tests to Diagnose Coronary Artery Disease
- Novel Blood Test Could Reduce Need for PET Imaging of Patients with Alzheimer’s
- CT-Based Deep Learning Algorithm Accurately Differentiates Benign From Malignant Vertebral Fractures
- Minimally Invasive Procedure Could Help Patients Avoid Thyroid Surgery
- Self-Driving Mobile C-Arm Reduces Imaging Time during Surgery
- AR Application Turns Medical Scans Into Holograms for Assistance in Surgical Planning
- Imaging Technology Provides Ground-Breaking New Approach for Diagnosing and Treating Bowel Cancer
- CT Coronary Calcium Scoring Predicts Heart Attacks and Strokes
- AI Model Detects 90% of Lymphatic Cancer Cases from PET and CT Images
- Breakthrough Technology Revolutionizes Breast Imaging
- State-Of-The-Art System Enhances Accuracy of Image-Guided Diagnostic and Interventional Procedures
- Catheter-Based Device with New Cardiovascular Imaging Approach Offers Unprecedented View of Dangerous Plaques
Channels
Radiography
view channel
Novel Breast Imaging System Proves As Effective As Mammography
Breast cancer remains the most frequently diagnosed cancer among women. It is projected that one in eight women will be diagnosed with breast cancer during her lifetime, and one in 42 women who turn 50... Read more
AI Assistance Improves Breast-Cancer Screening by Reducing False Positives
Radiologists typically detect one case of cancer for every 200 mammograms reviewed. However, these evaluations often result in false positives, leading to unnecessary patient recalls for additional testing,... Read more
MRI
view channel
World's First Whole-Body Ultra-High Field MRI Officially Comes To Market
The world's first whole-body ultra-high field (UHF) MRI has officially come to market, marking a remarkable advancement in diagnostic radiology. United Imaging (Shanghai, China) has secured clearance from the U.... Read more
World's First Sensor Detects Errors in MRI Scans Using Laser Light and Gas
MRI scanners are daily tools for doctors and healthcare professionals, providing unparalleled 3D imaging of the brain, vital organs, and soft tissues, far surpassing other imaging technologies in quality.... Read more
Diamond Dust Could Offer New Contrast Agent Option for Future MRI Scans
Gadolinium, a heavy metal used for over three decades as a contrast agent in medical imaging, enhances the clarity of MRI scans by highlighting affected areas. Despite its utility, gadolinium not only... Read more.jpg "Image: The emerging role of MRI alongside PSA testing is redefining prostate cancer diagnostics (Photo courtesy of 123RF)")
Combining MRI with PSA Testing Improves Clinical Outcomes for Prostate Cancer Patients
Prostate cancer is a leading health concern globally, consistently being one of the most common types of cancer among men and a major cause of cancer-related deaths. In the United States, it is the most... Read moreUltrasound
view channel
First AI-Powered POC Ultrasound Diagnostic Solution Helps Prioritize Cases Based On Severity
Ultrasound scans are essential for identifying and diagnosing various medical conditions, but often, patients must wait weeks or months for results due to a shortage of qualified medical professionals... Read more
Largest Model Trained On Echocardiography Images Assesses Heart Structure and Function
Foundation models represent an exciting frontier in generative artificial intelligence (AI), yet many lack the specialized medical data needed to make them applicable in healthcare settings.... Read more.jpg "Image: The Sonic Lumen Tomography (SLT) intravascular ultrasound system has received FDA 510(k) clearance (Photo courtesy of Provisio Medical)")
Groundbreaking Technology Enables Precise, Automatic Measurement of Peripheral Blood Vessels
The current standard of care of using angiographic information is often inadequate for accurately assessing vessel size in the estimated 20 million people in the U.S. who suffer from peripheral vascular disease.... Read more
Nuclear Medicine
view channel
New Imaging Technique Monitors Inflammation Disorders without Radiation Exposure
Imaging inflammation using traditional radiological techniques presents significant challenges, including radiation exposure, poor image quality, high costs, and invasive procedures. Now, new contrast... Read more
New SPECT/CT Technique Could Change Imaging Practices and Increase Patient Access
The development of lead-212 (212Pb)-PSMA–based targeted alpha therapy (TAT) is garnering significant interest in treating patients with metastatic castration-resistant prostate cancer. The imaging of 212Pb,... Read more
New Radiotheranostic System Detects and Treats Ovarian Cancer Noninvasively
Ovarian cancer is the most lethal gynecological cancer, with less than a 30% five-year survival rate for those diagnosed in late stages. Despite surgery and platinum-based chemotherapy being the standard... Read more
AI System Automatically and Reliably Detects Cardiac Amyloidosis Using Scintigraphy Imaging
Cardiac amyloidosis, a condition characterized by the buildup of abnormal protein deposits (amyloids) in the heart muscle, severely affects heart function and can lead to heart failure or death without... Read moreImaging IT
view channel
New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible
Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology
The global artificial intelligence (AI) in medical diagnostics market is expanding with early disease detection being one of its key applications and image recognition becoming a compelling consumer proposition... Read more
Industry News
view channel
Hologic Acquires UK-Based Breast Surgical Guidance Company Endomagnetics Ltd.
Hologic, Inc. (Marlborough, MA, USA) has entered into a definitive agreement to acquire Endomagnetics Ltd. (Cambridge, UK), a privately held developer of breast cancer surgery technologies, for approximately... Read more
Bayer and Google Partner on New AI Product for Radiologists
Medical imaging data comprises around 90% of all healthcare data, and it is a highly complex and rich clinical data modality and serves as a vital tool for diagnosing patients. Each year, billions of medical... Read more
