Study Shows IMRT Better for Head and Neck Cancer
By MedImaging International staff writers Posted on 31 Jul 2017 |
Image: The TomoTherapy system being used to treat a patient (Photo courtesy of Accuray).
A prospective, multi-center study has shown that IMRT cancer therapy provides a significantly improved cancer-specific survival rate, as well as improved post-treatment salivary function compared to volumetric modulated arc therapy.
Fourteen radiotherapy centers in France took part in the study comparing cancer-specific survival rates, and local cancer control rates, using Intensity-Modulated Radiation Therapy (IMRT), and volumetric modulated arc therapy. This is the first prospective study to compare clinical outcomes between radiation therapy platforms.
The results of the study were announced by Accuray (Sunnyvale, CA) and were published in the June 26, 2017, issue of the International Journal of Radiation Oncology – Biology – Physics. The researchers compared the Accuray TomoTherapy IMRT, and the Varian Medical Systems (Palo Alto, CA, USA) RapidArc systems in their study that included 166 patients.
The results showed that the TomoTherapy platform provided improved local control, cancer-specific survival, and function of the salivary gland. The researchers also monitored long-term toxicity, and salivary function, as well as loco-regional control. The benefit may be even more significant for the local control of larger tumors that have already spread to many lymph nodes.
Fabienne Hirigoyenberry-Lanson, VP Global Medical and Scientific Affairs of Accuray, said, "This landmark study demonstrates that the technique used to deliver IMRT can have a major impact on patient outcomes. Two key measures – the local control rate and cancer-specific survival rate – reinforce the TomoTherapy System's effectiveness in managing head and neck tumors, results we would also expect to see with the Radixact System, our next-generation TomoTherapy platform. And, importantly, salivary function was compromised after treatment in significantly fewer patients treated with TomoTherapy, even while they achieved better tumor control."
Related Links:
Accuray
Varian Medical Systems
Fourteen radiotherapy centers in France took part in the study comparing cancer-specific survival rates, and local cancer control rates, using Intensity-Modulated Radiation Therapy (IMRT), and volumetric modulated arc therapy. This is the first prospective study to compare clinical outcomes between radiation therapy platforms.
The results of the study were announced by Accuray (Sunnyvale, CA) and were published in the June 26, 2017, issue of the International Journal of Radiation Oncology – Biology – Physics. The researchers compared the Accuray TomoTherapy IMRT, and the Varian Medical Systems (Palo Alto, CA, USA) RapidArc systems in their study that included 166 patients.
The results showed that the TomoTherapy platform provided improved local control, cancer-specific survival, and function of the salivary gland. The researchers also monitored long-term toxicity, and salivary function, as well as loco-regional control. The benefit may be even more significant for the local control of larger tumors that have already spread to many lymph nodes.
Fabienne Hirigoyenberry-Lanson, VP Global Medical and Scientific Affairs of Accuray, said, "This landmark study demonstrates that the technique used to deliver IMRT can have a major impact on patient outcomes. Two key measures – the local control rate and cancer-specific survival rate – reinforce the TomoTherapy System's effectiveness in managing head and neck tumors, results we would also expect to see with the Radixact System, our next-generation TomoTherapy platform. And, importantly, salivary function was compromised after treatment in significantly fewer patients treated with TomoTherapy, even while they achieved better tumor control."
Related Links:
Accuray
Varian Medical Systems
Latest Radiography News
- Novel Breast Imaging System Proves As Effective As Mammography
- AI Assistance Improves Breast-Cancer Screening by Reducing False Positives
- AI Could Boost Clinical Adoption of Chest DDR
- 3D Mammography Almost Halves Breast Cancer Incidence between Two Screening Tests
- AI Model Predicts 5-Year Breast Cancer Risk from Mammograms
- Deep Learning Framework Detects Fractures in X-Ray Images With 99% Accuracy
- Direct AI-Based Medical X-Ray Imaging System a Paradigm-Shift from Conventional DR and CT
- Chest X-Ray AI Solution Automatically Identifies, Categorizes and Highlights Suspicious Areas
- AI Diagnoses Wrist Fractures As Well As Radiologists
- Annual Mammography Beginning At 40 Cuts Breast Cancer Mortality By 42%
- 3D Human GPS Powered By Light Paves Way for Radiation-Free Minimally-Invasive Surgery
- Novel AI Technology to Revolutionize Cancer Detection in Dense Breasts
- AI Solution Provides Radiologists with 'Second Pair' Of Eyes to Detect Breast Cancers
- AI Helps General Radiologists Achieve Specialist-Level Performance in Interpreting Mammograms
- Novel Imaging Technique Could Transform Breast Cancer Detection
- Computer Program Combines AI and Heat-Imaging Technology for Early Breast Cancer Detection