fMRI Study Reveals Older Patients Take Longer to Recover from Concussion
|
By MedImaging International staff writers Posted on 20 Oct 2015 |
|
A new study has shown that younger patients had hyperactivation in the precuneus and right inferior parietal gyrus of the brain during working memory tasks, while older patients had hypoactivation.
The results of the study were published online in the journal Radiology. The researchers used functional Magnetic Resonance Imaging (fMRI) to evaluate how the age of a patient affected the performance of working memory performance, and functional activation in the brain, following Mild Traumatic Brain Injury (MTBI).
The study included 13 patients aged 21–30 years, and 13 patients aged 51-68 years. All patients had been diagnosed with MTBI, and the researchers included 26 age- and gender-matched controls. The researchers performed the first fMRI scan one month or less after injury, and a follow-up scan six weeks after that. The researchers analyzed symptoms, working memory activity, and neuropsychological test results in all patients.
Concussion or Mild Traumatic Brain Injury (MTBI) accounts for 75% of TBI cases, and often results in difficulties with working memory. In most of these patients Computed Tomography (CT), and conventional Magnetic Resonance Imaging (MRI) do not reveal abnormal findings.
The results of the initial and follow-up study showed that young patients had a significantly lower post-concussion symptom score, at follow-up, compared to the initial exam, whereas no significant difference in the score was found in older patients, who also showed persistent hypo-activation. The results show that separate management strategies need to be developed for concussion injuries in different age groups.
Coauthor of the study, Ying-Chi Tseng, MD, Department of Radiology, Shuang-Ho Hospital, Taipei Medical University (New Taipei City, Taiwan), said, “Taken together, these findings provide evidence for differential neural plasticity across different ages, with potential prognostic and therapeutic implications. The results suggest that MTBI might cause a more profound and lasting effect in older patients.”
Related Links:
Shuang-Ho Hospital
The results of the study were published online in the journal Radiology. The researchers used functional Magnetic Resonance Imaging (fMRI) to evaluate how the age of a patient affected the performance of working memory performance, and functional activation in the brain, following Mild Traumatic Brain Injury (MTBI).
The study included 13 patients aged 21–30 years, and 13 patients aged 51-68 years. All patients had been diagnosed with MTBI, and the researchers included 26 age- and gender-matched controls. The researchers performed the first fMRI scan one month or less after injury, and a follow-up scan six weeks after that. The researchers analyzed symptoms, working memory activity, and neuropsychological test results in all patients.
Concussion or Mild Traumatic Brain Injury (MTBI) accounts for 75% of TBI cases, and often results in difficulties with working memory. In most of these patients Computed Tomography (CT), and conventional Magnetic Resonance Imaging (MRI) do not reveal abnormal findings.
The results of the initial and follow-up study showed that young patients had a significantly lower post-concussion symptom score, at follow-up, compared to the initial exam, whereas no significant difference in the score was found in older patients, who also showed persistent hypo-activation. The results show that separate management strategies need to be developed for concussion injuries in different age groups.
Coauthor of the study, Ying-Chi Tseng, MD, Department of Radiology, Shuang-Ho Hospital, Taipei Medical University (New Taipei City, Taiwan), said, “Taken together, these findings provide evidence for differential neural plasticity across different ages, with potential prognostic and therapeutic implications. The results suggest that MTBI might cause a more profound and lasting effect in older patients.”
Related Links:
Shuang-Ho Hospital
Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
New
1.5T MRI System
uMR 670
Thyroid Shield
Standard Thyroid Shield
New
Remote Controlled Digital Radiography and Fluoroscopy System
Eco Track-DRF - MARS 50/MARS50+/MARS 65/MARS 80
Latest Radiography News
- Novel Breast Imaging System Proves As Effective As Mammography
- AI Assistance Improves Breast-Cancer Screening by Reducing False Positives
- AI Could Boost Clinical Adoption of Chest DDR
- 3D Mammography Almost Halves Breast Cancer Incidence between Two Screening Tests
- AI Model Predicts 5-Year Breast Cancer Risk from Mammograms
- Deep Learning Framework Detects Fractures in X-Ray Images With 99% Accuracy
- Direct AI-Based Medical X-Ray Imaging System a Paradigm-Shift from Conventional DR and CT
- Chest X-Ray AI Solution Automatically Identifies, Categorizes and Highlights Suspicious Areas
- AI Diagnoses Wrist Fractures As Well As Radiologists
- Annual Mammography Beginning At 40 Cuts Breast Cancer Mortality By 42%
- 3D Human GPS Powered By Light Paves Way for Radiation-Free Minimally-Invasive Surgery
- Novel AI Technology to Revolutionize Cancer Detection in Dense Breasts
- AI Solution Provides Radiologists with 'Second Pair' Of Eyes to Detect Breast Cancers
- AI Helps General Radiologists Achieve Specialist-Level Performance in Interpreting Mammograms
- Novel Imaging Technique Could Transform Breast Cancer Detection
- Computer Program Combines AI and Heat-Imaging Technology for Early Breast Cancer Detection
Channels
Radiography
view channel
Novel Breast Imaging System Proves As Effective As Mammography
Breast cancer remains the most frequently diagnosed cancer among women. It is projected that one in eight women will be diagnosed with breast cancer during her lifetime, and one in 42 women who turn 50... Read more
AI Assistance Improves Breast-Cancer Screening by Reducing False Positives
Radiologists typically detect one case of cancer for every 200 mammograms reviewed. However, these evaluations often result in false positives, leading to unnecessary patient recalls for additional testing,... Read more
Ultrasound
view channel.jpg "Image: CAM figures of testing images (Photo courtesy of SPJ; DOI:10.34133/research.0319)")
Diagnostic System Automatically Analyzes TTE Images to Identify Congenital Heart Disease
Congenital heart disease (CHD) is one of the most prevalent congenital anomalies worldwide, presenting substantial health and financial challenges for affected patients. Early detection and treatment of... Read more
Super-Resolution Imaging Technique Could Improve Evaluation of Cardiac Conditions
The heart depends on efficient blood circulation to pump blood throughout the body, delivering oxygen to tissues and removing carbon dioxide and waste. Yet, when heart vessels are damaged, it can disrupt... Read more
First AI-Powered POC Ultrasound Diagnostic Solution Helps Prioritize Cases Based On Severity
Ultrasound scans are essential for identifying and diagnosing various medical conditions, but often, patients must wait weeks or months for results due to a shortage of qualified medical professionals... Read more
Nuclear Medicine
view channel
New PET Biomarker Predicts Success of Immune Checkpoint Blockade Therapy
Immunotherapies, such as immune checkpoint blockade (ICB), have shown promising clinical results in treating melanoma, non-small cell lung cancer, and other tumor types. However, the effectiveness of these... Read more![Image: Whole-body maximum-intensity projections over time after [68Ga]Ga-DPI-4452 administration (Photo courtesy of SNMMI)](https://globetechcdn.com/mobile_medicalimaging/images/stories/articles/article_images/2024-05-09/JNM May 2024 Hofman.jpg "Image: Whole-body maximum-intensity projections over time after [68Ga]Ga-DPI-4452 administration (Photo courtesy of SNMMI)"){kind=small}
New PET Agent Rapidly and Accurately Visualizes Lesions in Clear Cell Renal Cell Carcinoma Patients
Clear cell renal cell cancer (ccRCC) represents 70-80% of renal cell carcinoma cases. While localized disease can be effectively treated with surgery and ablative therapies, one-third of patients either... Read more
New Imaging Technique Monitors Inflammation Disorders without Radiation Exposure
Imaging inflammation using traditional radiological techniques presents significant challenges, including radiation exposure, poor image quality, high costs, and invasive procedures. Now, new contrast... Read more
New SPECT/CT Technique Could Change Imaging Practices and Increase Patient Access
The development of lead-212 (212Pb)-PSMA–based targeted alpha therapy (TAT) is garnering significant interest in treating patients with metastatic castration-resistant prostate cancer. The imaging of 212Pb,... Read moreGeneral/Advanced Imaging
view channel
Bone Density Test Uses Existing CT Images to Predict Fractures
Osteoporotic fractures are not only devastating and deadly, especially hip fractures, but also impose significant costs. They rank among the top chronic diseases in terms of disability-adjusted life years... Read more
AI Predicts Cardiac Risk and Mortality from Routine Chest CT Scans
Heart disease remains the leading cause of death and is largely preventable, yet many individuals are unaware of their risk until it becomes severe. Early detection through screening can reveal heart issues,... Read more
Imaging IT
view channel
New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible
Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology
The global artificial intelligence (AI) in medical diagnostics market is expanding with early disease detection being one of its key applications and image recognition becoming a compelling consumer proposition... Read more
Industry News
view channel
Hologic Acquires UK-Based Breast Surgical Guidance Company Endomagnetics Ltd.
Hologic, Inc. (Marlborough, MA, USA) has entered into a definitive agreement to acquire Endomagnetics Ltd. (Cambridge, UK), a privately held developer of breast cancer surgery technologies, for approximately... Read more
Bayer and Google Partner on New AI Product for Radiologists
Medical imaging data comprises around 90% of all healthcare data, and it is a highly complex and rich clinical data modality and serves as a vital tool for diagnosing patients. Each year, billions of medical... Read more
