Lower Mortality Rates Shown with LDCT Screening

A new study has shown that by combining Low-Dose CT (LDCT) lung cancer screening program with robust programs that help people stop smoking can reduce mortality rates, and be cost-effective.

The researchers used OncoSim-LC, a microsimulation model to compare screening scenarios with smoking-cessation, to those without a cessation program, and projected this over 20 years.


The findings were presented by researchers from the McMaster University (Hamilton, ON, Canada) at the 18th World Conference on Lung Cancer (WCLC) organized by the International Association for the Study of Lung Cancer (IASLC), in Yokohama, Japan. The results of OncoSim-LC microsimulation model study showed that by adding a smoking-cessation program to an organized LDCT screening program was relatively cost effective, and resulted in significantly fewer deaths.

Additional research is required to determine the structure of such joint programs, to determine the detailed economic requirements, and to ensure that participants continue to adhere to both LDCT and smoking cessation programs.

Dr. William Evans, from the McMaster University, said, "To achieve the maximal benefits of a LDCT screening program, it is essential to incorporate a robust smoking cessation intervention. In my long career as an oncologist, I have not been able to save any patients from advanced non-small cell lung cancer. I believe that an organized lung screening program can be used to provide teachable moments for heavy smokers and, ultimately, save lives."

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